SFI1 and FAM131C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SFI1	FAM131C
Description		SFI1 centrin binding protein	family with sequence similarity 131 member C
Image			No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol
	Molecular Function	Protein Binding Phosphatase Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphatase Activity Ciliary Basal Body-plasma Membrane Docking
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483) Type 2 diabetes ( 31118516)	Cognitive performance ( 19734545) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		14 interacting genes: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH GOLGA2 KRT19 LPXN MAD2L2 MDFI RADIL RBPMS SERTAD1	10 interacting genes: APP DNAJA3 EWSR1 GRN HPCAL4 LMO3 MAD1L1 NDN SFI1 VSNL1
Entrez ID		9814	348487
HPRD ID		11550	08779
Ensembl ID		ENSG00000198089	ENSG00000185519
Uniprot IDs		A8K8P3	Q96AQ9
PDB IDs		2K2I
Enriched GO Terms of Interacting Partners?
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