SERTAD2 and TFDP1

Number of citations of the paper that reports this interaction (PubMedID 11331592)
35

Data Source:
HPRD (in vitro)

		SERTAD2	TFDP1
Description		SERTA domain containing 2	transcription factor Dp-1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol RNA Polymerase II Transcription Factor Complex
	Molecular Function	Transcription Coactivator Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding
	Biological Process	Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Epidermis Development Anoikis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of G0 To G1 Transition Negative Regulation Of Fat Cell Proliferation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of DNA Biosynthetic Process
Pathways			Activation of NOXA and translocation to mitochondria Inhibition of replication initiation of damaged DNA by RB1/E2F1 Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Activation of PUMA and translocation to mitochondria G0 and Early G1 Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Oxidative Stress Induced Senescence Oncogene Induced Senescence TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Cyclin E associated events during G1/S transition G1/S-Specific Transcription G1/S-Specific Transcription Cyclin D associated events in G1 Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by E2F6 Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 29403010 27863252) Monocyte percentage of white cells ( 27863252) Red cell distribution width ( 27863252 28957414) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Visceral fat ( 22589738)	Height ( 31562340) Mild influenza (H1N1) infection ( 26379185)
Interacting Genes		8 interacting genes: CEP68 CREBBP E2F1 KAT2B SUPT7L TFDP1 TRIM28 XPO1	17 interacting genes: CDK1 CDK2 CDK6 CDKN2A CREBBP E2F1 E2F2 E2F3 E2F4 E2F5 E2F6 NPDC1 SERTAD2 SIAH1 SOCS3 TP53 TP53BP1
Entrez ID		9792	7027
HPRD ID		18040	01792
Ensembl ID		ENSG00000179833	ENSG00000198176
Uniprot IDs		Q14140	A0A024RDY4 Q14186
PDB IDs			2AZE 5GOW 5TUU 5TUV
Enriched GO Terms of Interacting Partners?
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