RAPGEF5 and TMEM253

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

		RAPGEF5	TMEM253
Description		Rap guanine nucleotide exchange factor 5	transmembrane protein 253
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Integral Component Of Membrane
	Molecular Function	Ras Guanyl-nucleotide Exchange Factor Activity Rap Guanyl-nucleotide Exchange Factor Activity GTP-dependent Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Nervous System Development
Pathways
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Diastolic blood pressure ( 30224653) Glaucoma ( 30104761) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Night sleep phenotypes ( 27126917) Spatial processing ( 31596458) Squamous cell lung carcinoma ( 28604730) Thyroid stimulating hormone levels ( 17903292)
Interacting Genes		7 interacting genes: MRAS PLAC9 RAP1A RAP2A RAP2B TMEM253 VANGL1	2 interacting genes: RAPGEF5 TUBA1B
Entrez ID		9771	643382
HPRD ID		15208
Ensembl ID		ENSG00000136237	ENSG00000232070
Uniprot IDs		A8MQ07 Q5JPD2 Q92565	P0C7T8
PDB IDs		1WGY
Enriched GO Terms of Interacting Partners?
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