RAB11FIP3 and ARF4

Number of citations of the paper that reports this interaction (PubMedID 11481332)
45

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		RAB11FIP3	ARF4
Description		RAB11 family interacting protein 3	ADP ribosylation factor 4
Image
GO Annotations	Cellular Component	Nucleoplasm Endosome Centrosome Cytosol Endocytic Vesicle Midbody Cleavage Furrow Centriolar Satellite Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane	Cytoplasm Golgi Apparatus Cytosol Membrane Ruffle Membrane Dendritic Spine Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Calcium Ion Binding Protein Binding Rab GTPase Binding ADP-ribosylation Factor Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding	GTPase Activity ARF Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding
	Biological Process	Cell Cycle Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Cell Division Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion	Protein ADP-ribosylation Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Epidermal Growth Factor Receptor Signaling Pathway Brain Development Learning Vesicle-mediated Transport Cell Migration Activation Of Phospholipase D Activity Negative Regulation Of Apoptotic Process Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Dendritic Spine Development Protein Localization To Cilium Regulation Of Postsynapse Organization Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		VxPx cargo-targeting to cilium	VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Platelet count ( 27863252) Platelet distribution width ( 27863252)
Interacting Genes		9 interacting genes: ARF4 ARF5 ARF6 ASAP1 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34	13 interacting genes: ADRB2 APBA1 APBA2 APBA3 EGFR HNRNPD IKBKG PTEN RAB11FIP3 RCHY1 RHOA SDCBP2 SIRPA
Entrez ID		9727	378
HPRD ID		18521	03107
Ensembl ID		ENSG00000090565	ENSG00000168374
Uniprot IDs		O75154	P18085
PDB IDs		2D7C 2HV8 4D0M 4UJ3 4UJ4	1Z6X
Enriched GO Terms of Interacting Partners?
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