ARF4 and SDCBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARF4	SDCBP2
Description		ADP ribosylation factor 4	syndecan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Membrane Ruffle Membrane Dendritic Spine Extracellular Exosome Glutamatergic Synapse	Nucleolus Cytoplasm Plasma Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	GTPase Activity ARF Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Protein ADP-ribosylation Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Epidermal Growth Factor Receptor Signaling Pathway Brain Development Learning Vesicle-mediated Transport Cell Migration Activation Of Phospholipase D Activity Negative Regulation Of Apoptotic Process Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Dendritic Spine Development Protein Localization To Cilium Regulation Of Postsynapse Organization Regulation Of Reactive Oxygen Species Metabolic Process	Nervous System Development Cell Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways		VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: ADRB2 APBA1 APBA2 APBA3 EGFR HNRNPD IKBKG PTEN RAB11FIP3 RCHY1 RHOA SDCBP2 SIRPA	44 interacting genes: ADAP1 ARF4 BEND7 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR MED4 NFASC NKAPD1 NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 RPL22 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 TRAF1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		378	27111
HPRD ID		03107	18032
Ensembl ID		ENSG00000168374	ENSG00000125775
Uniprot IDs		P18085	Q9H190
PDB IDs		1Z6X
Enriched GO Terms of Interacting Partners?
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