TGS1 and COIL

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TGS1	COIL
Description		trimethylguanosine synthase 1	coilin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Small Nuclear Ribonucleoprotein Complex	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body
	Molecular Function	Protein Binding RNA Methyltransferase Activity RNA Trimethylguanosine Synthase Activity	Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly 7-methylguanosine RNA Capping Regulation Of Lipid Metabolic Process Ribonucleoprotein Complex Biogenesis 7-methylguanosine Cap Hypermethylation	Spliceosomal SnRNP Assembly
Pathways		RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression snRNP Assembly PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Height ( 18391951) Serum thyroid-stimulating hormone levels ( 24852370)	Height ( 18391951)
Interacting Genes		6 interacting genes: COIL CREBBP EED EP300 HNF4A NCOA6	70 interacting genes: ACTN1 ACTN2 ACTN4 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP CCDC136 CCDC159 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 ELOA2 FGF12 FHL5 FXR2 GCC1 KALRN KAZN KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MFAP1 MYO5B NIF3L1 NOLC1 NTAQ1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 POLR2L PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 WDR34 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		96764	8161
HPRD ID		07567	02605
Ensembl ID		ENSG00000137574	ENSG00000121058
Uniprot IDs		Q96RS0	P38432
PDB IDs		3EGI 3GDH
Enriched GO Terms of Interacting Partners?
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