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TGS1

Description trimethylguanosine synthase 1
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Cytoplasm
  • Cytosol
  • Cajal Body
  • Small Nuclear Ribonucleoprotein Complex
Molecular Function
  • Protein Binding
  • RNA Methyltransferase Activity
  • RNA Trimethylguanosine Synthase Activity
Biological Process
  • Spliceosomal SnRNP Assembly
  • 7-methylguanosine RNA Capping
  • Regulation Of Lipid Metabolic Process
  • Ribonucleoprotein Complex Biogenesis
  • 7-methylguanosine Cap Hypermethylation
Pathways
  • RORA activates gene expression
  • BMAL1:CLOCK,NPAS2 activates circadian gene expression
  • snRNP Assembly
  • PPARA activates gene expression
  • PPARA activates gene expression
  • Transcriptional activation of mitochondrial biogenesis
  • Activation of gene expression by SREBF (SREBP)
  • Transcriptional regulation of white adipocyte differentiation
  • Regulation of lipid metabolism by PPARalpha
  • Circadian Clock
Drugs
Diseases
GWAS
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Height ( 18391951)
  • Serum thyroid-stimulating hormone levels ( 24852370)
Interacting Genes 6 interacting genes: COIL CREBBP EED EP300 HNF4A NCOA6
Entrez ID 96764
HPRD ID 07567
Ensembl ID ENSG00000137574
Uniprot IDs Q96RS0
PDB IDs 3EGI 3GDH
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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