PDE4DIP and ADH1B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PDE4DIP	ADH1B
Description		phosphodiesterase 4D interacting protein	alcohol dehydrogenase 1B (class I), beta polypeptide
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril	Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Enzyme Binding Molecular Adaptor Activity	Alcohol Dehydrogenase Activity, Zinc-dependent Retinol Dehydrogenase Activity Zinc Ion Binding
	Biological Process	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization	Retinoid Metabolic Process Ethanol Oxidation Retinol Metabolic Process Retinoic Acid Metabolic Process
Pathways			Ethanol oxidation
Drugs			NADH Fomepizole N-Benzylformamide 4-Iodopyrazole 2'-Monophosphoadenosine 5'-Diphosphoribose Cyclohexanol N-Heptylformamide Glycerin
Diseases
GWAS		Capecitabine sensitivity ( 22864933)	Alcohol consumption ( 23743675 28937693 31358974) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Alcohol consumption (drinks per week) ( 28485404 30643258 30679032) Alcohol consumption in current drinkers ( 28937693) Alcohol dependence ( 24166409 23456092 28714907 31591379 31090166 22004471) Alcohol dependence (desire to cut drinking) ( 31090166) Alcohol dependence (tolerance) ( 31090166) Alcohol dependence symptom count ( 31090166) Alcohol use disorder ( 30940813) Alcohol use disorder (consumption score) ( 30940813 30336701) Alcohol use disorder (dependence and problematic use scores) ( 30336701) Bitter alcoholic beverage consumption ( 31046077) Blood urea nitrogen levels ( 31152163) Esophageal cancer ( 19698717) Esophageal cancer (alcohol interaction) ( 22960999) Heel bone mineral density ( 30598549) Initial pursuit acceleration ( 29064472) Lung cancer ( 28604730) Maximum habitual alcohol consumption ( 31151762) Metabolite levels ( 23823483) Oral cavity and pharyngeal cancer ( 21437268 27749845) Oral cavity cancer ( 27749845) Oropharynx cancer ( 27749845) Regular attendance at a pub or social club ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Urinary sodium excretion ( 31409800)
Interacting Genes		76 interacting genes: ADH1B AEN ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CHD1L EGR2 EIF4E2 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GBE1 GFI1B GNRHR2 GOLGA5 GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT1 KRT18 KRT31 LAMTOR3 LENG1 LMO4 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RBM8A RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 THRB TK1 TMOD4 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZDHHC17 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26	5 interacting genes: IRAK3 PDE4DIP PML RACK1 SERPINA3
Entrez ID		9659	125
HPRD ID		10482	00065
Ensembl ID		ENSG00000178104	ENSG00000196616
Uniprot IDs		A0A075B749 A0A087WYE4 Q5VU43	D6RHZ6 P00325 V9HW50
PDB IDs			1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD
Enriched GO Terms of Interacting Partners?
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