CHD1L and CTCF

Number of citations of the paper that reports this interaction (PubMedID 24725430)
6

Data Source:
BioGRID (two hybrid)

		CHD1L	CTCF
Description		chromodomain helicase DNA binding protein 1 like	CCCTC-binding factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus
	Molecular Function	Nucleotide Binding DNA Helicase Activity Protein Binding ATP Binding ATPase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Nucleotide-excision Repair, DNA Duplex Unwinding DNA Repair Nucleotide-excision Repair, Preincision Complex Stabilization Nucleotide-excision Repair, Preincision Complex Assembly Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Chromatin Remodeling Cellular Response To DNA Damage Stimulus Nucleotide-excision Repair, DNA Incision Global Genome Nucleotide-excision Repair	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Chromosome Segregation Negative Regulation Of Cell Proliferation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centromeric Sister Chromatid Cohesion Protein Localization To Chromosome, Centromeric Region
Pathways		Formation of Incision Complex in GG-NER Dual Incision in GG-NER	Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Height ( 31562340) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25760438)	Elevated fasting plasma glucose ( 30004843) HDL cholesterol ( 19060911)
Interacting Genes		6 interacting genes: BAALC CTCF NR4A1 PDE4DIP SCYL1 SRPK2	19 interacting genes: CHD1L CHD7 CHD8 HMGB1 MT-ND4 PARP1 POLR2A RAD51 RALA RHOU RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRB YBX1 ZMYM4
Entrez ID		9557	10664
HPRD ID		09880	05005
Ensembl ID		ENSG00000131778	ENSG00000102974
Uniprot IDs		A0A0A0MRH8 A0A0A0MSH9 Q86WJ1	A0A2R8YFL0 P49711
PDB IDs			1X6H 2CT1 5K5H 5K5I 5K5J 5K5L 5KKQ 5T00 5T0U 5UND 5YEF 5YEG 5YEH 5YEL
Enriched GO Terms of Interacting Partners?
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