EIF4E2 and SAG

		EIF4E2	SAG
Description		eukaryotic translation initiation factor 4E family member 2	S-antigen visual arrestin
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytosol Membrane
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding	G Protein-coupled Receptor Binding Opsin Binding Protein Phosphatase Inhibitor Activity Phosphoprotein Binding
	Biological Process	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation	G Protein-coupled Receptor Internalization Cell Surface Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Phosphoprotein Phosphatase Activity
Pathways		ISG15 antiviral mechanism	Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases			Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO) Retinitis pigmentosa (RP)
GWAS		Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520)	Calcium levels ( 20705733) Crohn's disease ( 22412388) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9	4 interacting genes: ADRA1B CHRM2 EIF4E2 RHO
Entrez ID		9470	6295
HPRD ID		05798	01625
Ensembl ID		ENSG00000135930	ENSG00000130561
Uniprot IDs		B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1	P10523
PDB IDs		2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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