SAG and ADRA1B

Number of citations of the paper that reports this interaction (PubMedID 8617782)
35

Data Source:
HPRD (in vivo)

		SAG	ADRA1B
Description		S-antigen visual arrestin	adrenoceptor alpha 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytosol Membrane	Cell Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Caveola Nuclear Membrane
	Molecular Function	G Protein-coupled Receptor Binding Opsin Binding Protein Phosphatase Inhibitor Activity Phosphoprotein Binding	Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	G Protein-coupled Receptor Internalization Cell Surface Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Phosphoprotein Phosphatase Activity	Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Behavior Intracellular Signal Transduction Glucose Homeostasis Positive Regulation Of MAPK Cascade Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Cardiac Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Pathways		Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade	Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events
Drugs			Amphetamine Midodrine Ziprasidone Cabergoline Dapiprazole Amitriptyline Olanzapine Alfuzosin Clozapine Norepinephrine Mirtazapine Phenylephrine Loxapine Promazine Prazosin Imipramine Chlorpromazine Chlorpromazine Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Thioridazine Phentolamine Ergotamine Tamsulosin Methoxamine Trimipramine Risperidone Modafinil Propiomazine Fenoldopam Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Carvedilol Doxepin Nefazodone Desipramine Terazosin Pergolide Bromocriptine Quetiapine Aripiprazole Lisdexamfetamine Paliperidone Mephentermine Methotrimeprazine Dextroamphetamine Phendimetrazine Propericiazine Acepromazine Thioproperazine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Silodosin Droxidopa Xylometazoline Perospirone Brexpiprazole Dosulepin Etoperidone Cirazoline Synephrine Tiapride
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO) Retinitis pigmentosa (RP)
GWAS		Calcium levels ( 20705733) Crohn's disease ( 22412388) Estimated glomerular filtration rate ( 31152163)	Diastolic blood pressure ( 27841878) Plasma anti-thyroglobulin levels ( 29678681) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		4 interacting genes: ADRA1B CHRM2 EIF4E2 RHO	11 interacting genes: ADRA1A AP2M1 EZR FLNC GNA11 GNAQ NOS1 PPP1R9B PRKCA SAG STAT1
Entrez ID		6295	147
HPRD ID		01625	00080
Ensembl ID		ENSG00000130561	ENSG00000170214
Uniprot IDs		P10523	P35368
PDB IDs
Enriched GO Terms of Interacting Partners?
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