TGFBRAP1 and EIF4E2

		TGFBRAP1	EIF4E2
Description		transforming growth factor beta receptor associated protein 1	eukaryotic translation initiation factor 4E family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Membrane CORVET Complex Intracellular Membrane-bounded Organelle	Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Transforming Growth Factor Beta Receptor Binding Protein Binding SMAD Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Regulation Of Transcription, DNA-templated Intracellular Protein Transport Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Endosome To Lysosome Transport Vesicle-mediated Transport Endosomal Vesicle Fusion	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation
Pathways			ISG15 antiviral mechanism
Drugs
Diseases
GWAS		AIDS ( 19754311) Body mass index ( 26426971) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Menarche (age at onset) ( 27182965) Obesity-related traits ( 23251661) Preeclampsia ( 23551011)	Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520)
Interacting Genes		10 interacting genes: ACVR1B ACVR2B ACVRL1 ALOX5 BMPR1A EIF4E2 SMAD2 SMAD4 TGFBR1 TGFBR2	51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		9392	9470
HPRD ID		06948	05798
Ensembl ID		ENSG00000135966	ENSG00000135930
Uniprot IDs		Q8WUH2	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs			2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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