NUMBL and ESRP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NUMBL	ESRP2
Description		NUMB like endocytic adaptor protein	epithelial splicing regulatory protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Cadherin Binding	RNA Binding MRNA Binding
	Biological Process	Nervous System Development Axonogenesis Cytokine-mediated Signaling Pathway Protein Metabolic Process Lateral Ventricle Development Neuroblast Division In Subventricular Zone Adherens Junction Organization Positive Regulation Of Neurogenesis	Alternative MRNA Splicing, Via Spliceosome Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Epithelial Cell Proliferation Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis
Pathways			FGFR2 alternative splicing
Drugs
Diseases
GWAS		Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Kawasaki disease ( 22446962) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730)	Schizophrenia ( 25056061 29483656)
Interacting Genes		23 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 YWHAG	2 interacting genes: CYB5B NUMBL
Entrez ID		9253	80004
HPRD ID		04931	07971
Ensembl ID		ENSG00000105245	ENSG00000103067
Uniprot IDs		A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0	Q9H6T0
PDB IDs		3F0W
Enriched GO Terms of Interacting Partners?
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