ESRP2 and NUMBL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ESRP2	NUMBL
Description		epithelial splicing regulatory protein 2	NUMB like endocytic adaptor protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm
	Molecular Function	RNA Binding MRNA Binding	Protein Binding Cadherin Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Epithelial Cell Proliferation Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis	Nervous System Development Axonogenesis Cytokine-mediated Signaling Pathway Protein Metabolic Process Lateral Ventricle Development Neuroblast Division In Subventricular Zone Adherens Junction Organization Positive Regulation Of Neurogenesis
Pathways		FGFR2 alternative splicing
Drugs
Diseases
GWAS		Schizophrenia ( 25056061 29483656)	Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Kawasaki disease ( 22446962) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730)
Interacting Genes		2 interacting genes: CYB5B NUMBL	23 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 YWHAG
Entrez ID		80004	9253
HPRD ID		07971	04931
Ensembl ID		ENSG00000103067	ENSG00000105245
Uniprot IDs		Q9H6T0	A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0
PDB IDs			3F0W
Enriched GO Terms of Interacting Partners?
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