VAPB and VAMP1

Number of citations of the paper that reports this interaction (PubMedID 9920726)
49

Data Source:
HPRD (in vitro)

		VAPB	VAMP1
Description		VAMP associated protein B and C	vesicle associated membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cell Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Exit Site	Mitochondrial Outer Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Cell Junction Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane SNARE Complex Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Tertiary Granule Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Microtubule Binding Enzyme Binding FFAT Motif Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Beta-tubulin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Cellular Calcium Ion Homeostasis ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Modulation By Virus Of Host Morphology Or Physiology Sphingolipid Biosynthetic Process Endoplasmic Reticulum Unfolded Protein Response IRE1-mediated Unfolded Protein Response Positive Regulation Of Viral Genome Replication Endoplasmic Reticulum-plasma Membrane Tethering COPII-coated Vesicle Budding Endoplasmic Reticulum Membrane Organization	Vesicle Fusion Synaptic Vesicle Priming Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane SNARE Complex Assembly
Pathways		Sphingolipid de novo biosynthesis	Toxicity of botulinum toxin type D (BoNT/D) Toxicity of botulinum toxin type F (BoNT/F) Toxicity of botulinum toxin type G (BoNT/G)
Drugs			Botulinum Toxin Type B
Diseases		Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD) Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS			Hip geometry ( 17903296)
Interacting Genes		16 interacting genes: AQP2 EMD GLP1R GPR25 KCNB1 MTNR1A OSBPL2 STX1A STX2 STX4 STX5 USP20 VAMP1 VAMP2 VHL VKORC1	12 interacting genes: BCAP31 CDKN2A DNAJC5 KASH5 LMNA SNAP23 SNAP29 STX1A STX1B STX4 VAPA VAPB
Entrez ID		9217	6843
HPRD ID		09300	01716
Ensembl ID		ENSG00000124164	ENSG00000139190
Uniprot IDs		O95292 Q53XM7	F5GZV7 P23763
PDB IDs		2MDK 3IKK
Enriched GO Terms of Interacting Partners?
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