ZMYM4 and CTCF

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZMYM4	CTCF
Description		zinc finger MYM-type containing 4	CCCTC-binding factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Multicellular Organism Development Regulation Of Cell Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Chromosome Segregation Negative Regulation Of Cell Proliferation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centromeric Sister Chromatid Cohesion Protein Localization To Chromosome, Centromeric Region
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Night sleep phenotypes ( 27126917)	Elevated fasting plasma glucose ( 30004843) HDL cholesterol ( 19060911)
Interacting Genes		7 interacting genes: CTCF FHL2 H3-4 ROR2 RUNX1T1 SRPK2 SUMO2	19 interacting genes: CHD1L CHD7 CHD8 HMGB1 MT-ND4 PARP1 POLR2A RAD51 RALA RHOU RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRB YBX1 ZMYM4
Entrez ID		9202	10664
HPRD ID		10326	05005
Ensembl ID		ENSG00000146463	ENSG00000102974
Uniprot IDs		Q5VZL5	A0A2R8YFL0 P49711
PDB IDs			1X6H 2CT1 5K5H 5K5I 5K5J 5K5L 5KKQ 5T00 5T0U 5UND 5YEF 5YEG 5YEH 5YEL
Enriched GO Terms of Interacting Partners?
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