EOLA1 and NPC2

		EOLA1	NPC2
Description		endothelium and lymphocyte associated ASCH domain 1	NPC intracellular cholesterol transporter 2
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GO Annotations	Cellular Component		Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Cholesterol Binding Enzyme Binding Sterol Binding Intermembrane Cholesterol Transfer Activity
	Biological Process	Regulation Of Gene Expression Regulation Of Interleukin-6 Production	Cholesterol Metabolic Process Response To Virus Phospholipid Transport Sterol Transport Regulation Of Isoprenoid Metabolic Process Cholesterol Transport Intracellular Sterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Neutrophil Degranulation Glycolipid Transport
Pathways			Neutrophil degranulation LDL clearance
Drugs
Diseases			Niemann-Pick type C disease (NPC), including: Niemann-Pick disease, type C1; Niemann-Pick disease, type C2
GWAS			Advanced glycation end-product levels ( 26915486) Blood protein levels ( 29875488) Intraocular pressure ( 31959993)
Interacting Genes		3 interacting genes: MT2A NPC2 NUP88	19 interacting genes: AREL1 BARD1 BRCA1 CTSW DHDDS ECT2 EIF2B2 EOLA1 ERRFI1 LIG4 PAXIP1 PDIA6 SCNN1A SCRN1 SSR1 TMED10 TRIM14 USP4 VASH1
Entrez ID		91966	10577
HPRD ID		06625	03008
Ensembl ID		ENSG00000197620	ENSG00000119655
Uniprot IDs		Q8TE69	A0A024R6C0 P61916
PDB IDs		5Y7D	5KWY
Enriched GO Terms of Interacting Partners?
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