MPP5 and LIN7A

Number of citations of the paper that reports this interaction (PubMedID 10753959)
48

Data Source:
HPRD (in vitro)

		MPP5	LIN7A
Description		membrane palmitoylated protein 5	lin-7 homolog A, crumbs cell polarity complex component
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Apical Plasma Membrane Axon Protein-containing Complex Myelin Sheath Adaxonal Region Perikaryon Lateral Loop Schmidt-Lanterman Incisure Extracellular Exosome	Cell Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse Extracellular Exosome MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding ATP Binding Protein Domain Specific Binding	Protein Binding L27 Domain Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Transport Inner Ear Development Protein-containing Complex Assembly Protein Localization To Basolateral Plasma Membrane
Pathways		Tight junction interactions	Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS			Age-related cataracts (age at onset) ( 25352737) Dental caries ( 23259602)
Interacting Genes		8 interacting genes: ARF6 CRB3 LIN7A MPP4 NEK9 PARD6B PATJ SOCS4	19 interacting genes: ABCA1 ADGRB1 APP BAIAP2 CASK DLG2 DLG3 DLG4 DNAJC5 FAM9B GOLGA2 GRIN2B KCNJ12 MPP3 MPP5 MPP6 NOTCH2NLA SLC6A12 ZYX
Entrez ID		64398	8825
HPRD ID		09508	04542
Ensembl ID		ENSG00000072415	ENSG00000111052
Uniprot IDs		Q658X5 Q8N3R9	O14910
PDB IDs		1Y76 3UIT 4UU5 4UU6 4WSI
Enriched GO Terms of Interacting Partners?
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