PDCD5 and NUDT3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		PDCD5	NUDT3
Description		programmed cell death 5	nudix hydrolase 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding Heparin Binding Acetyltransferase Activator Activity Beta-tubulin Binding	Magnesium Ion Binding Endopolyphosphatase Activity Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity
	Biological Process	Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways			Synthesis of pyrophosphates in the cytosol
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252) Metabolite levels ( 23823483) Red cell distribution width ( 27863252)	Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412)
Interacting Genes		12 interacting genes: ACP5 CEP126 EEF1G GGCX KAT5 KDM1A LRIF1 NUDT3 OTUD5 UBE2D3 UTP14A VHL	36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		9141	11165
HPRD ID		06843	14849
Ensembl ID		ENSG00000105185	ENSG00000272325
Uniprot IDs		O14737	O95989
PDB IDs		1YYB 2CRU 2K6B	2FVV 2Q9P
Enriched GO Terms of Interacting Partners?
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