CACNA1H and USP5

Number of citations of the paper that reports this interaction (PubMedID 25889575)
18

Data Source:
BioGRID (affinity chromatography technology, unspecified method)

		CACNA1H	USP5
Description		calcium voltage-gated channel subunit alpha1 H	ubiquitin specific peptidase 5
Image		No pdb structure
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Calcium Channel Complex Integral Component Of Membrane Neuron Projection	Lysosome Cytosol
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Cation Channel Activity Protein Binding Low Voltage-gated Calcium Channel Activity Metal Ion Binding Scaffold Protein Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding
	Biological Process	Muscle Contraction Muscle Organ Development Myoblast Fusion Regulation Of Heart Contraction Neuronal Action Potential Aldosterone Biosynthetic Process Cellular Response To Hormone Stimulus Cortisol Biosynthetic Process Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Cellular Response To Potassium Ion Regulation Of Membrane Potential Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential Inorganic Cation Transmembrane Transport Positive Regulation Of Acrosome Reaction	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Deubiquitination
Pathways		NCAM1 interactions	Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs		Isradipine Spironolactone Cinnarizine Zonisamide Felodipine Nitrendipine Nifedipine Amiodarone Bepridil Mibefradil Flunarizine Trimebutine Manidipine
Diseases
GWAS		Blood protein levels ( 28240269)
Interacting Genes		3 interacting genes: GNG2 KCNMA1 USP5	23 interacting genes: APP CACNA1H DAZAP2 DVL2 PJA1 PLA2G2A RFFL RNF11 SMURF1 STK33 TADA3 TMEM239 TRAF6 TRIM26 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIML1 UBE2S UBTD2 USP28
Entrez ID		8912	8078
HPRD ID		07442	03265
Ensembl ID		ENSG00000196557	ENSG00000111667
Uniprot IDs		A0A1W2PQW2 B3KQH9 O95180	A0A140VJZ1 P45974
PDB IDs			2DAG 2DAK 2G43 2G45 3IHP 6DXH 6DXT 6NFT 6P9G
Enriched GO Terms of Interacting Partners?
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