TAX1BP1 and AZI2

Number of citations of the paper that reports this interaction (PubMedID 30459273)
2

Data Source:
BioGRID (x-ray crystallography, pull down, affinity chromatography technology)

		TAX1BP1	AZI2
Description		Tax1 binding protein 1	5-azacytidine induced 2
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytoplasm
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	Protein Binding
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	Mitotic Cell Cycle I-kappaB Kinase/NF-kappaB Signaling Viral Process Interferon-alpha Production Interferon-gamma Production Interleukin-6 Production Tumor Necrosis Factor Production T Cell Activation Dendritic Cell Proliferation Dendritic Cell Differentiation
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Cognitive decline (age-related) ( 28078323)
Interacting Genes		40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC	12 interacting genes: APBA3 FAM107A IKBKE MIB1 MTPAP N4BP1 RNF31 TAX1BP1 TBK1 TICAM1 TRAF3 TXLNA
Entrez ID		8887	64343
HPRD ID		05618	10577
Ensembl ID		ENSG00000106052	ENSG00000163512
Uniprot IDs		B4DSG5 Q86VP1	Q9H6S1
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G	5EP6 5Z7G 5Z7L
Enriched GO Terms of Interacting Partners?
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