AZI2 and TAX1BP1

Number of citations of the paper that reports this interaction (PubMedID 30459273)
2

Data Source:
BioGRID (x-ray crystallography, pull down, affinity chromatography technology)

		AZI2	TAX1BP1
Description		5-azacytidine induced 2	Tax1 binding protein 1
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GO Annotations	Cellular Component	Cytoplasm	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle I-kappaB Kinase/NF-kappaB Signaling Viral Process Interferon-alpha Production Interferon-gamma Production Interleukin-6 Production Tumor Necrosis Factor Production T Cell Activation Dendritic Cell Proliferation Dendritic Cell Differentiation	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process
Pathways			Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323)	Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: APBA3 FAM107A IKBKE MIB1 MTPAP N4BP1 RNF31 TAX1BP1 TBK1 TICAM1 TRAF3 TXLNA	40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC
Entrez ID		64343	8887
HPRD ID		10577	05618
Ensembl ID		ENSG00000163512	ENSG00000106052
Uniprot IDs		Q9H6S1	B4DSG5 Q86VP1
PDB IDs		5EP6 5Z7G 5Z7L	2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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