RIOK3 and CREB3L3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RIOK3	CREB3L3
Description		RIO kinase 3	cAMP responsive element binding protein 3 like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Preribosome, Small Subunit Precursor	Golgi Membrane Nuclear Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Caspase Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding CAMP Response Element Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Protein Phosphorylation Chromosome Segregation Maturation Of SSU-rRNA Negative Regulation Of Protein Complex Assembly Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus Cellular Response To DsRNA Cellular Response To Virus Cellular Response To DsDNA	Positive Regulation Of Acute Inflammatory Response Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	CREB3 factors activate genes Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		8 interacting genes: BCL2L11 CASP10 CDC42 CREB3L3 FBXO25 PAK2 SMURF1 UBC	12 interacting genes: ATF6 BAD CEBPG CREB3 CREB3L1 CSNK2A1 GSK3B KHDRBS1 KPNA2 PELI2 RIOK3 USP7
Entrez ID		8780	84699
HPRD ID		04659	16752
Ensembl ID		ENSG00000101782	ENSG00000060566
Uniprot IDs		B0YJ89 B4E1Q4 O14730	Q68CJ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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