BECN1 and ATG3

Number of citations of the paper that reports this interaction (PubMedID 24186333)
8

Data Source:
BioGRID (pull down)

		BECN1	ATG3
Description		beclin 1	autophagy related 3
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Cell Nucleus Mitochondrion Endosome Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endosome Membrane Extrinsic Component Of Membrane Mitochondrial Membrane Phosphatidylinositol 3-kinase Complex, Class III, Type I Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III	Cytoplasmic Ubiquitin Ligase Complex Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Phosphatidylinositol 3-kinase Binding GTPase Binding	Protein Binding Atg8 Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Endocytosis Autophagy Apoptotic Process Cellular Defense Response Cellular Response To Nitrogen Starvation Mitotic Metaphase Plate Congression Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Viral Process Macroautophagy Protein Deubiquitination Protein Localization By The Cvt Pathway Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Early Endosome To Late Endosome Transport Late Endosome To Vacuole Transport Cell Division Defense Response To Virus Negative Regulation Of Cell Death Response To Mitochondrial Depolarisation Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Protein Modification Process Protein Targeting To Membrane Macroautophagy Protein Ubiquitination Mitochondrial Fragmentation Involved In Apoptotic Process Autophagy Of Nucleus Negative Regulation Of Phagocytosis Regulation Of Cilium Assembly
Pathways		Macroautophagy Ub-specific processing proteases	Macroautophagy
Drugs		Estradiol
Diseases
GWAS		Type 2 diabetes (age of onset) ( 28060188)	Asthma (childhood onset) ( 23829686)
Interacting Genes		50 interacting genes: AKT1 AMBRA1 ARAF ARNT ATG3 BCL2 BCL2L1 BTK CASP3 CCND2 CDK4 CDK6 CDKN2A CDKN2B EPHA2 ERBB2 FGFR4 FRS2 FZR1 GFI1B GLIS2 GOPC GRM1 ITCH KAT2A KDELR2 LATS2 MAP2K3 MAP2K5 MAP2K6 MAPKAPK2 MAPKAPK3 MDM4 NF2 PDGFRA PGK1 RACK1 RAF1 SHD SMAD2 STK11 TEAD2 TERT TRAF2 TSC1 UBC ULK1 WASHC1 XPO1 YES1	6 interacting genes: ATG12 ATG7 BECN1 GABARAP GABARAPL2 MAP1LC3B
Entrez ID		8678	64422
HPRD ID		05087	10654
Ensembl ID		ENSG00000126581	ENSG00000144848
Uniprot IDs		A0A024R1X5 B4DQ36 E7EV84 Q14457 W0FFG4	Q9NT62
PDB IDs		2P1L 2PON 3DVU 4DDP 4MI8 5EFM 5HHE 5VAU 5VAX 5VAY 6DCN 6DCO 6HOI 6HOJ 6HOK	4NAW
Enriched GO Terms of Interacting Partners?
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