CBFA2T3 and SEC24A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CBFA2T3	SEC24A
Description		CBFA2/RUNX1 partner transcriptional co-repressor 3	SEC24 homolog A, COPII coat complex component
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat
	Molecular Function	DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Protein Binding Zinc Ion Binding
	Biological Process	Response To Hypoxia Negative Regulation Of Cell Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cholesterol Homeostasis Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process COPII Vesicle Coating Positive Regulation Of Protein Secretion Cargo Loading Into COPII-coated Vesicle
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Mean corpuscular hemoglobin ( 27863252) Mean platelet volume ( 27863252) Multiple sclerosis ( 31604244) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)
Interacting Genes		15 interacting genes: CBFA2T2 GMEB2 HDAC1 HDAC3 MATN2 NUP98 PRKAR2A RUNX1 RUNX1T1 SEC24A TCF3 ZBTB33 ZBTB38 ZBTB4 ZNF652	4 interacting genes: CBFA2T3 EWSR1 TFG TRIP13
Entrez ID		863	10802
HPRD ID		04847	08456
Ensembl ID		ENSG00000129993	ENSG00000113615
Uniprot IDs		O75081	B4E205 O95486
PDB IDs			2NUP 2NUT 3EGD 3EGX 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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