KRTAP2-4 and PTPMT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRTAP2-4	PTPMT1
Description		keratin associated protein 2-4	protein tyrosine phosphatase mitochondrial 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Nucleus Mitochondrial Inner Membrane
	Molecular Function	Protein Binding	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity
	Biological Process	Keratinization	Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Keratinization Keratinization	Synthesis of PG
Drugs
Diseases
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010) Hypertension ( 27618448) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean arterial pressure ( 27618448) Mood instability ( 31168069) Neuroticism ( 29255261) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		11 interacting genes: ADAMTSL3 CBX2 CNNM3 KRTAP10-1 KRTAP10-5 PTPMT1 RPS28 SDC3 SHFL TMEM190 ZNF587	16 interacting genes: KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP2-4 KRTAP5-9 KRTAP9-2 MAPK6 MDFI MTUS2 NOTCH2NLA RGS20 SIAH1 TAB1 TRIM27
Entrez ID		85294	114971
HPRD ID		13936	15151
Ensembl ID		ENSG00000213417	ENSG00000110536
Uniprot IDs		P0C7H8 Q9BYR9	Q8WUK0
PDB IDs
Enriched GO Terms of Interacting Partners?
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