PTPMT1 and KRTAP2-4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PTPMT1	KRTAP2-4
Description		protein tyrosine phosphatase mitochondrial 1	keratin associated protein 2-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrial Inner Membrane	Cytosol Keratin Filament
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity	Protein Binding
	Biological Process	Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway	Keratinization
Pathways		Synthesis of PG	Keratinization Keratinization
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010) Hypertension ( 27618448) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean arterial pressure ( 27618448) Mood instability ( 31168069) Neuroticism ( 29255261) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		16 interacting genes: KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP2-4 KRTAP5-9 KRTAP9-2 MAPK6 MDFI MTUS2 NOTCH2NLA RGS20 SIAH1 TAB1 TRIM27	11 interacting genes: ADAMTSL3 CBX2 CNNM3 KRTAP10-1 KRTAP10-5 PTPMT1 RPS28 SDC3 SHFL TMEM190 ZNF587
Entrez ID		114971	85294
HPRD ID		15151	13936
Ensembl ID		ENSG00000110536	ENSG00000213417
Uniprot IDs		Q8WUK0	P0C7H8 Q9BYR9
PDB IDs
Enriched GO Terms of Interacting Partners?
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