RALBP1 and HSF1

Number of citations of the paper that reports this interaction (PubMedID 12621024)
40

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)

		RALBP1	HSF1
Description		ralA binding protein 1	heat shock transcription factor 1
Image
GO Annotations	Cellular Component	Cytosol Membrane	Kinetochore Condensed Chromosome Kinetochore Nuclear Chromatin Euchromatin Heterochromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol PML Body Pronucleus Perinuclear Region Of Cytoplasm Nuclear Stress Granule Mitotic Spindle Pole Chaperone Complex Ribonucleoprotein Complex
	Molecular Function	GTPase Activator Activity Protein Binding Ral GTPase Binding Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity Rac GTPase Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Chromatin DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein Self-association Protein Heterodimerization Activity Hsp90 Protein Binding Translation Elongation Factor Binding STAT Family Protein Binding Sequence-specific Single Stranded DNA Binding Promoter-specific Chromatin Binding
	Biological Process	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Drug Transmembrane Export	Negative Regulation Of Transcription By RNA Polymerase II MAPK Cascade Embryonic Placenta Development DNA Repair MRNA Processing Defense Response Female Meiotic Nuclear Division Spermatogenesis Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation MRNA Transcription Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Response To Activity Viral Process Negative Regulation Of Protein Complex Assembly Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Cellular Response To Heat Cellular Response To Unfolded Protein Cellular Protein-containing Complex Assembly Cellular Response To Potassium Ion Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Embryonic Process Involved In Female Pregnancy Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Heat Stress Cellular Response To Hydrogen Peroxide Cellular Response To Lipopolysaccharide Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Estradiol Stimulus Cellular Response To Gamma Radiation Cellular Response To Diamide Negative Regulation Of Inclusion Body Assembly Positive Regulation Of Inclusion Body Assembly Positive Regulation Of Cold-induced Thermogenesis Regulation Of Cellular Response To Heat Positive Regulation Of MRNA Polyadenylation Negative Regulation Of Neuron Death Positive Regulation Of Apoptotic DNA Fragmentation Cellular Response To Sodium Arsenite Cellular Response To Angiotensin Positive Regulation Of Microtubule Binding Cellular Response To Nitroglycerin Cellular Response To L-glutamine Response To Hypobaric Hypoxia Response To Psychosocial Stress Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		Rho GTPase cycle	Regulation of HSF1-mediated heat shock response HSF1 activation Attenuation phase HSF1-dependent transactivation Aggrephagy
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)	Dupuytren's disease ( 28886342)
Interacting Genes		30 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GSE1 HOOK2 HSF1 IKBKG PLCG2 PPL PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 TSFM ZBTB38 ZNF707	50 interacting genes: CAMK2A CDC20 CDK6 CEBPB CHST10 CREBBP CSNK2A1 DAXX DNAJB1 EEF1D ENO2 FILIP1 FKBP4 FKBP5 GSK3A GTF2A2 GTF2B HSBP1 HSF2 HSP90AA1 HSP90AB1 HSPA1A HSPA8 MAPK1 MAPK3 MAPK8 MAPK9 MAPKAPK2 NCOA6 PPID PRKDC PTGES3 RALBP1 REPS1 RNF20 SMARCA4 STAT1 STUB1 SUB1 SUMO1 SUMO3 SYMPK TAF1 TAF7 TAF9 TBP UBE2I XRCC5 XRCC6 YWHAE
Entrez ID		10928	3297
HPRD ID		09013	00778
Ensembl ID		ENSG00000017797	ENSG00000185122
Uniprot IDs		Q15311	Q00613
PDB IDs		2KWH 2KWI 2MBG	2LDU 5D5U 5D5V 5HDG 5HDN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?