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PCGF1 and CBX6

  • Number of citations of the paper that reports this interaction (PubMedID 21282530)
  • 40
  • Data Source:
  • BioGRID (pull down)

PCGF1

CBX6

Description polycomb group ring finger 1 chromobox 6
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • PcG Protein Complex
  • PRC1 Complex
  • Heterochromatin
  • Nucleus
  • Nucleoplasm
  • PcG Protein Complex
Molecular Function
  • Protein Binding
  • Protein C-terminus Binding
  • Metal Ion Binding
  • Promoter-specific Chromatin Binding
  • Single-stranded RNA Binding
  • Protein Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Chromatin Silencing
  • Regulation Of Transcription, DNA-templated
  • Histone H2A Monoubiquitination
  • Histone H2A-K119 Monoubiquitination
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Chromatin Organization
Pathways
  • Oxidative Stress Induced Senescence
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
  • Bladder cancer ( 24163127 20972438)
Interacting Genes 10 interacting genes: BCOR CALCOCO2 CBX6 CBX7 MUC7 PCGF5 RNF125 TRIM55 UBE2D3 UBE2U 6 interacting genes: HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6
Entrez ID 84759 23466
HPRD ID 11404 13005
Ensembl ID ENSG00000115289 ENSG00000183741
Uniprot IDs Q9BSM1 B0QXZ6 O95503
PDB IDs 4HPL 4HPM 5JH5 3GV6 3I90
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025

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