PPP1R9B and ADRA2B

Number of citations of the paper that reports this interaction (PubMedID 11154706)
39

Data Source:
BioGRID (pull down)

		PPP1R9B	ADRA2B
Description		protein phosphatase 1 regulatory subunit 9B	adrenoceptor alpha 2B
Image		No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Nucleoplasm Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Filopodium Dendrite Growth Cone Cortical Actin Cytoskeleton Ruffle Membrane Neuronal Cell Body Dendritic Spine Neck Dendritic Spine Head Cytoplasmic Side Of Dendritic Spine Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Protein Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein C-terminus Binding Protein Phosphatase 1 Binding Kinase Binding D2 Dopamine Receptor Binding Ion Channel Binding Actin Filament Binding	Adrenergic Receptor Activity Alpha2-adrenergic Receptor Activity Protein Binding Epinephrine Binding
	Biological Process	Regulation Of Cell Growth By Extracellular Stimulus Regulation Of Protein Phosphorylation Response To Amphetamine Developmental Process Involved In Reproduction Protein Phosphorylation Actin Filament Organization Cell Cycle Arrest Regulation Of Exit From Mitosis Aging Learning RNA Splicing Dendrite Development Cell Migration Calcium-mediated Signaling Hippocampus Development Cerebral Cortex Development Actin Filament Depolymerization Negative Regulation Of Cell Growth Neuron Projection Development Negative Regulation Of Phosphoprotein Phosphatase Activity Response To Prostaglandin E Response To Nicotine Response To Immobilization Stress Regulation Of Cell Proliferation Filopodium Assembly Response To Steroid Hormone Modulation Of Chemical Synaptic Transmission Male Mating Behavior Reproductive System Development Cellular Response To Morphine Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Estradiol Stimulus Response To Clozapine Cellular Response To Peptide Positive Regulation Of Protein Localization To Plasma Membrane Protein Localization To Actin Cytoskeleton Positive Regulation Of Protein Localization To Actin Cortical Patch Response To Kainic Acid Response To L-phenylalanine Derivative Protein Localization To Cell Periphery Regulation Of Opioid Receptor Signaling Pathway	Activation Of MAPK Activity Regulation Of Vascular Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Female Pregnancy Behavior Negative Regulation Of Norepinephrine Secretion Platelet Activation Activation Of Protein Kinase B Activity Negative Regulation Of Epinephrine Secretion Receptor Transactivation Positive Regulation Of MAPK Cascade Positive Regulation Of Neuron Differentiation Positive Regulation Of Blood Pressure Positive Regulation Of Uterine Smooth Muscle Contraction Adrenergic Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Pathways			Adrenoceptors Adrenaline signalling through Alpha-2 adrenergic receptor G alpha (i) signalling events G alpha (z) signalling events
Drugs			Amphetamine Bethanidine Ziprasidone Cabergoline Ropinirole Etomidate Olanzapine Clozapine Norepinephrine Phenylpropanolamine Loxapine Pramipexole Prazosin Chlorpromazine Brimonidine Nortriptyline Amoxapine Clonidine Lisuride Guanabenz Epinephrine Ergotamine Tizanidine Apomorphine Trimipramine Risperidone Tolazoline Fenoldopam Dobutamine Phenoxybenzamine Maprotiline Oxymetazoline Apraclonidine Guanfacine Ergoloid mesylate Carvedilol Doxepin Desipramine Pergolide Bromocriptine Quetiapine Aripiprazole Paliperidone Ephedra Mephentermine Yohimbine Methotrimeprazine Methamphetamine Dronedarone Rotigotine OPC-28326 Epicept NP-1 Mianserin Asenapine Droxidopa Esmirtazapine Xylometazoline Levonordefrin Dosulepin Etoperidone Cirazoline Setiptiline Tiapride
Diseases
GWAS		Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		23 interacting genes: ACTA1 ADRA1A ADRA1B ADRA2A ADRA2B ADRA2C CCKAR CCKBR CDKN2A CHRM3 DCX DRD2 MAPK1 PPP1CA PPP1CB PPP1CC PPP1R2 PPP1R9A PRKACA RGS2 RPS6KB1 TGOLN2 TIAM1	9 interacting genes: ADAMTS1 EIF2B1 GGA1 GGA2 GGA3 GNAI2 PPP1R9B UCHL1 YWHAZ
Entrez ID		84687	151
HPRD ID		04506	00086
Ensembl ID		ENSG00000108819	ENSG00000274286
Uniprot IDs		Q96SB3	P18089
PDB IDs			2CVA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?