SMARCA5 and MAF

Number of citations of the paper that reports this interaction (PubMedID 16675956)
58

Data Source:
HPRD (in vivo)

		SMARCA5	MAF
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	MAF bZIP transcription factor
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex NURF Complex RSF Complex Nuclear Replication Fork	Chromatin Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity ATPase Activity Nucleosome Binding Histone Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Chromatin Silencing At RDNA Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning CENP-A Containing Nucleosome Assembly ATP-dependent Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor	Negative Regulation Of Transcription By RNA Polymerase II Cytokine Production Transcription By RNA Polymerase II Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Inner Ear Development Lens Fiber Cell Differentiation
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere	RUNX2 regulates osteoblast differentiation
Drugs		Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases			Multiple myeloma
GWAS		Height ( 31562340)	Alzheimer's disease (late onset) ( 30820047) Colorectal cancer ( 30529582) Depressive symptoms (SSRI exposure interaction) ( 25649181) Estimated glomerular filtration rate ( 31015462) Height ( 20668459) Lysophosphatidylcholine levels ( 31551469) Macular thickness ( 30535121) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602 21833088) Obesity ( 19151714) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Renal function-related traits (urea) ( 22797727) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Serum alkaline phosphatase levels ( 29403010) Serum thyroid-stimulating hormone levels ( 24852370) Serum uric acid levels ( 30993211) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335) Thyroid volume ( 21565293) Urate levels ( 23263486)
Interacting Genes		17 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3-3A H3C1 H4-16 HDAC2 MAF POLE3 RAD21 RSF1 SATB1	17 interacting genes: ATF4 CREBBP EP300 ETS1 FOS FOSL1 HOXD12 JUN MAFA MAFB MAFG MYB NEU1 SMARCA5 SOX9 UBE2O USF2
Entrez ID		8467	4094
HPRD ID		04538	01518
Ensembl ID		ENSG00000153147	ENSG00000178573
Uniprot IDs		O60264	H3BP11 O75444
PDB IDs		6NE3
Enriched GO Terms of Interacting Partners?
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