MAP1LC3A and RETREG3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MAP1LC3A	RETREG3
Description		microtubule associated protein 1 light chain 3 alpha	reticulophagy regulator family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse	Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation	Positive Regulation Of Neuron Projection Development
Pathways		Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241)	Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		49 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG101 ATG13 ATG4B BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV NBR1 NEDD4 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RB1CC1 RDH12 RETREG3 RTKN SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TUBA4A ULK1	9 interacting genes: ABHD16A ARHGAP27 ARL6IP1 GABARAPL1 KANSL1 MAP1LC3A RUNDC1 SPPL2C STAP1
Entrez ID		84557	162427
HPRD ID		03144	14108
Ensembl ID		ENSG00000101460	ENSG00000141699
Uniprot IDs		Q9H492	K7EQI9 Q86VR2
PDB IDs		3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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