RETREG3 and SPPL2C

		RETREG3	SPPL2C
Description		reticulophagy regulator family member 3	signal peptide peptidase like 2C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Protein-containing Complex	Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi-associated Vesicle Membrane Integral Component Of Cytoplasmic Side Of Endoplasmic Reticulum Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Aspartic Endopeptidase Activity, Intramembrane Cleaving Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Neuron Projection Development	Membrane Protein Ectodomain Proteolysis Membrane Protein Intracellular Domain Proteolysis Membrane Protein Proteolysis
Pathways
Drugs
Diseases
GWAS		Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Alcohol use disorder (total score) ( 30336701) Chronic obstructive pulmonary disease ( 30804561) Hand grip strength ( 29691431) Idiopathic pulmonary fibrosis ( 24429156) Male-pattern baldness ( 28196072) Neuroticism ( 29255261) Parkinson's disease ( 28892059) Red blood cell count ( 27863252)
Interacting Genes		9 interacting genes: ABHD16A ARHGAP27 ARL6IP1 GABARAPL1 KANSL1 MAP1LC3A RUNDC1 SPPL2C STAP1	1 interacting genes: RETREG3
Entrez ID		162427	162540
HPRD ID		14108	07085
Ensembl ID		ENSG00000141699	ENSG00000185294
Uniprot IDs		K7EQI9 Q86VR2	Q8IUH8
PDB IDs
Enriched GO Terms of Interacting Partners?
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