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LZTS2 and HSPD1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
381
Data Source:
BioGRID
(two hybrid, two hybrid, two hybrid)
LZTS2
HSPD1
Description
leucine zipper tumor suppressor 2
heat shock protein family D (Hsp60) member 1
Image
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Microtubule
Plasma Membrane
Midbody
Vesicle
Extracellular Space
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Early Endosome
Peroxisomal Matrix
Rough Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Plasma Membrane
Clathrin-coated Pit
Cell Surface
Membrane
Mitochondrial Crista
Coated Vesicle
Secretory Granule
Protein-containing Complex
Zymogen Granule
Membrane Raft
Lipopolysaccharide Receptor Complex
Extracellular Exosome
Molecular Function
Protein Binding
Lipopolysaccharide Binding
Protease Binding
P53 Binding
DNA Replication Origin Binding
Single-stranded DNA Binding
RNA Binding
Double-stranded RNA Binding
Protein Binding
ATP Binding
High-density Lipoprotein Particle Binding
Isomerase Activity
ATPase Activity
Enzyme Binding
Ubiquitin Protein Ligase Binding
Apolipoprotein Binding
Apolipoprotein A-I Binding
Insulin Binding
Unfolded Protein Binding
Chaperone Binding
Modification-dependent Protein Binding
Biological Process
Mitotic Cytokinesis
Negative Regulation Of Cell Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Primary Ureteric Bud Growth
Ureter Morphogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Response To Hypoxia
B Cell Cytokine Production
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell
Response To Ischemia
Regulation Of Transcription By RNA Polymerase II
'de Novo' Protein Folding
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Unfolded Protein
Apoptotic Mitochondrial Changes
Response To Cold
Response To Activity
Viral Process
Response To Lipopolysaccharide
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-6 Production
Response To ATP
Cellular Response To Heat
Protein Refolding
B Cell Proliferation
T Cell Activation
B Cell Activation
Response To Cocaine
Response To Hydrogen Peroxide
Positive Regulation Of Macrophage Activation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Response To Estrogen
Adhesion Of Symbiont To Host
Protein Import Into Mitochondrial Intermembrane Space
Isotype Switching To IgG Isotypes
Positive Regulation Of Inflammatory Response
Protein Stabilization
Positive Regulation Of T Cell Activation
Chaperone-mediated Protein Complex Assembly
Response To Glucocorticoid
Protein Maturation
Interaction With Symbiont
Negative Regulation Of Apoptotic Process In Bone Marrow
Cellular Response To Interleukin-7
Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Positive Regulation Of Tumor Necrosis Factor Secretion
Positive Regulation Of Interleukin-6 Secretion
Pathways
Mitochondrial protein import
Mitochondrial protein import
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Copper
Diseases
Hereditary spastic paraplegia (SPG)
Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Ejection fraction in Tripanosoma cruzi seropositivity (
24324551
)
Regular attendance at a pub or social club (
29970889
)
Autism spectrum disorder or schizophrenia (
28540026
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
176 interacting genes:
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARHGAP32
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P1
BYSL
C1orf109
C8orf33
CARD9
CBX8
CCDC198
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CEP57L1
CFAP206
CHCHD3
CLIP4
CNNM3
COPB1
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DYRK2
EHHADH
EIF3D
EIF4E2
FAM107A
FAM124B
FAM161A
FAM74A4
FANCL
FEM1C
FGF12
FKBP6
FNDC11
FRG1
FRMD6
GATA1
GCC1
GEM
GFI1B
GLIDR
GMCL2
GNL3L
GPANK1
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HOXB9
HSPD1
IQCE
IQCN
KAT5
KAZN
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
MAB21L3
MAGEB4
MEMO1
MORF4L1
MORF4L2
MORN3
MOS
MTA1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
NTAQ1
OTUB2
PAK5
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R16A
PPP1R18
PQBP1
PRKAB2
PRPF31
PSMA1
QARS1
RAC1
RAD51D
RAMAC
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3RF2
SHFL
SLC15A3
SLC25A6
SLU7
SMARCB1
SMIM3
SNHG11
SNW1
SNX31
SPATA2
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
TBC1D7
TCEA2
TCHP
TEAD4
THAP10
THAP7
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TTC23
TXNL4A
USF2
USP2
UTP14C
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
47 interacting genes:
ALDH2
APP
BAK1
BRCA1
CA2
CASP3
CASP9
CEP70
CLEC7A
CLU
DHFR
ERG
FAM107A
FHIT
H2BC21
HSPE1
ITGA3
ITGB1
KRT31
KRT40
KRTAP10-3
KRTAP10-8
KRTAP5-9
LRRK2
LZTS2
MAPK6
MCPH1
NOS1AP
NOTCH2NLA
NR3C1
PLCG2
PLG
PPP2R1A
PPP2R1B
PRKACA
PRNP
PTEN
PTPN11
RASA1
RGS20
SAMD3
SUMO4
SUPT6H
TLR1
TMCC2
TRIM63
YWHAG
Entrez ID
84445
3329
HPRD ID
14341
00318
Ensembl ID
ENSG00000107816
ENSG00000144381
Uniprot IDs
B4DP66
Q9BRK4
A0A024R3X4
P10809
PDB IDs
4PJ1
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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