STX7 and DNAJC5

Number of citations of the paper that reports this interaction (PubMedID 29997244)
3

Data Source:
BioGRID (fluorescent resonance energy transfer)

		STX7	DNAJC5
Description		syntaxin 7	DnaJ heat shock protein family (Hsp40) member C5
Image		No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways			Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Prostate cancer ( 23535732)
Interacting Genes		15 interacting genes: CREB3 DNAJC5 ENTPD2 LMNA MAPK6 NAPA SNAP29 STX6 STX8 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		8417	80331
HPRD ID		04449	08539
Ensembl ID		ENSG00000079950	ENSG00000101152
Uniprot IDs		O15400	Q6AHX3 Q9H3Z4
PDB IDs			2N04 2N05
Enriched GO Terms of Interacting Partners?
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