BCAR3 and PSMC3IP

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BCAR3	PSMC3IP
Description		BCAR3 adaptor protein, NSP family member	PSMC3 interacting protein
Image			No pdb structure
GO Annotations	Cellular Component		Nucleoplasm
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	DNA Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Endothelin Receptor Signaling Pathway	Reciprocal Meiotic Recombination Positive Regulation Of Nucleic Acid-templated Transcription
Pathways			Meiotic recombination
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)	Colorectal or endometrial cancer ( 26621817)
Interacting Genes		29 interacting genes: AGR3 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCL5 CST6 DKK3 EPSTI1 ERBB2 ERBB3 ERRFI1 GLCE GREB1 HOXC6 KPNA1 MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP VPS45	20 interacting genes: AR AURKA BCAR3 BRMS1 CASP8 CHEK2 ERBB2 ESR1 ESR2 FGFR4 FZR1 NOTCH2 NR3C1 PIK3CA PSMC3 RB1CC1 RXRA TGFB1 THRB XRCC3
Entrez ID		8412	29893
HPRD ID		05268	16362
Ensembl ID		ENSG00000137936	ENSG00000131470
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	A0A158RUX1 K7ERB6 Q9P2W1
PDB IDs		3T6A
Enriched GO Terms of Interacting Partners?
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