BCAR3 and CST6

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BCAR3	CST6
Description		BCAR3 adaptor protein, NSP family member	cystatin E/M
Image
GO Annotations	Cellular Component		Cornified Envelope Extracellular Exosome
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	Cysteine-type Endopeptidase Inhibitor Activity
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Endothelin Receptor Signaling Pathway	Epidermis Development Anatomical Structure Morphogenesis Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576 29875488) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340)
Interacting Genes		29 interacting genes: AGR3 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCL5 CST6 DKK3 EPSTI1 ERBB2 ERBB3 ERRFI1 GLCE GREB1 HOXC6 KPNA1 MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP VPS45	6 interacting genes: BCAR3 GSK3B NOTCH2 PALB2 RAD51 TGFB1
Entrez ID		8412	1474
HPRD ID		05268	03535
Ensembl ID		ENSG00000137936	ENSG00000175315
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	Q15828
PDB IDs		3T6A	4N6L 4N6M 4N6N 4N6O 6FK0
Enriched GO Terms of Interacting Partners?
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