ARL6 and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 10508919)
10

Data Source:
HPRD (two hybrid)

		ARL6	ARL6IP1
Description		ADP ribosylation factor like GTPase 6	ADP ribosylation factor like GTPase 6 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat Extracellular Exosome	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Targeting To Membrane Intracellular Protein Transport Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Vesicle-mediated Transport Melanosome Transport Fat Cell Differentiation Protein Polymerization Cilium Assembly Protein Localization To Cilium Protein Localization To Non-motile Cilium Protein Transport From Ciliary Membrane To Plasma Membrane	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS) Retinitis pigmentosa (RP)
GWAS		Male infertility ( 19478329)
Interacting Genes		6 interacting genes: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B	41 interacting genes: ACSF2 ARL4D ARL6 CERT1 DIABLO FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 HGS HMGCL INPP5K LMNA MTERF3 MYG1 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RETREG3 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391
Entrez ID		84100	23204
HPRD ID		10588	09641
Ensembl ID		ENSG00000113966	ENSG00000170540
Uniprot IDs		Q9H0F7	A0A024QYV7 Q15041
PDB IDs		2H57
Enriched GO Terms of Interacting Partners?
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