ULK1 and GABARAP

Number of citations of the paper that reports this interaction (PubMedID 11146101)
49

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo, two hybrid)

		ULK1	GABARAP
Description		unc-51 like autophagy activating kinase 1	GABA type A receptor-associated protein
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Mitochondrial Outer Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Membrane Axon Guanyl-nucleotide Exchange Factor Complex Phagophore Assembly Site Membrane Recycling Endosome Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane Extrinsic Component Of Autophagosome Membrane Atg1/ULK1 Kinase Complex	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Rab GTPase Binding Identical Protein Binding Protein-containing Complex Binding GTPase Binding	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Autophagosome Assembly Protein Phosphorylation Autophagy Signal Transduction Protein Localization Regulation Of Autophagy Positive Regulation Of Autophagy Macroautophagy Regulation Of Macroautophagy Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Neuron Projection Regeneration Neuron Projection Development Negative Regulation Of Protein Complex Assembly Cellular Response To Nutrient Levels Response To Starvation Protein Autophosphorylation Axon Extension Autophagy Of Host Cells Involved In Interaction With Symbiont Positive Regulation Of Autophagosome Assembly	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Autophagosome Maturation
Pathways		Macroautophagy TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs Receptor Mediated Mitophagy	Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mercury levels ( 26025379)
Interacting Genes		23 interacting genes: ATG13 ATG9A BECN1 EXOC8 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C MAPK14 MBP MEFV MUL1 NEDD4L OCLN PPP1CA PRKAA1 SDCBP SMCR8 SYNGAP1 UBC USP20	51 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 NBR1 NEDD4 NSF OPTN PCM1 PGS1 PKP4 RB1CC1 RETREG1 SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TUBB3 ULK1 ULK2 VPS28
Entrez ID		8408	11337
HPRD ID		11933	05496
Ensembl ID		ENSG00000177169	ENSG00000170296
Uniprot IDs		O75385	O95166 Q6IAW1
PDB IDs		4WNO 4WNP 5CI7 6HYO 6MNH 6QAS	1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO
Enriched GO Terms of Interacting Partners?
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