GABARAP and PCM1

Number of citations of the paper that reports this interaction (PubMedID 28712572)
20

Data Source:
BioGRID (unspecified method)

		GABARAP	PCM1
Description		GABA type A receptor-associated protein	pericentriolar material 1
Image
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Protein-containing Complex Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Non-motile Cilium
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	Protein Binding Identical Protein Binding
	Biological Process	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Autophagosome Maturation	G2/M Transition Of Mitotic Cell Cycle Neuron Migration Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Social Behavior Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Neurogenesis Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Population Maintenance Ciliary Basal Body-plasma Membrane Docking Non-motile Cilium Assembly
Pathways		Macroautophagy TBC/RABGAPs	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Atrial fibrillation ( 28416818) Economic and political preferences ( 22566634) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Waist-hip ratio ( 30108283) Weight ( 28552196)
Interacting Genes		51 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 NBR1 NEDD4 NSF OPTN PCM1 PGS1 PKP4 RB1CC1 RETREG1 SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TUBB3 ULK1 ULK2 VPS28	39 interacting genes: ABI1 ABI2 AKAP9 BBS4 CASK CCDC172 CCHCR1 CDC42 CEP72 DDIT3 DDX23 DYNLL1 E2F4 ECPAS EPS8 EXOC8 FXR2 GABARAP GOLGA2 HAP1 ING5 KLC1 KLC4 KRT15 KRT19 KRT24 NDC80 NECAB2 PCNT PRC1 PRKCI RBM5 RINT1 RPA2 TFIP11 TTC8 WASHC3 YWHAE YWHAQ
Entrez ID		11337	5108
HPRD ID		05496	02624
Ensembl ID		ENSG00000170296	ENSG00000078674
Uniprot IDs		O95166 Q6IAW1	A2RUU9 B9EIS5 Q15154
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO	6HYL 6HYM
Enriched GO Terms of Interacting Partners?
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