OBSCN and MYH2

Number of citations of the paper that reports this interaction (PubMedID 15013951)
31

Data Source:
HPRD (in vivo)

		OBSCN	MYH2
Description		obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	myosin heavy chain 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Nuclear Body Myofibril Z Disc M Band Sarcolemma	Cytosol Muscle Myosin Complex Cell-cell Junction Myofibril Sarcomere Myosin Filament Protein-containing Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Calmodulin Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Structural Constituent Of Muscle Phosphatidylinositol-5-phosphate Binding Ankyrin Binding Titin Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Protein Localization To M-band Positive Regulation Of Apoptotic Process Sarcomere Organization Regulation Of Small GTPase Mediated Signal Transduction	Muscle Contraction Muscle Filament Sliding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433) PR interval ( 30046033)
Interacting Genes		7 interacting genes: ANK1 ANK2 BRCA1 CALM1 MTDH MYH2 TTN	6 interacting genes: AMPD1 DGKD OBSCN PRKCE PTK2B S100A4
Entrez ID		84033	4620
HPRD ID		10551	01173
Ensembl ID		ENSG00000154358	ENSG00000125414
Uniprot IDs		A6NGQ3 Q5VST9	Q9UKX2
PDB IDs		1V1C 2CR6 2DKU 2DM7 2E7B 2EDF 2EDH 2EDL 2EDQ 2EDR 2EDT 2EDW 2ENY 2EO1 2GQH 2MWC 2N56 2YZ8 4C4K 4RSV 4UOW 5TZM 6MG9
Enriched GO Terms of Interacting Partners?
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