CAPZB and BCCIP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPZB	BCCIP
Description		capping actin protein of muscle Z-line subunit beta	BRCA2 and CDKN1A interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Extracellular Exosome WASH Complex	Cell Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding	RNA Binding Protein Binding Tubulin Binding Kinase Regulator Activity
	Biological Process	Cell Morphogenesis ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization DNA Repair Cellular Response To DNA Damage Stimulus Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Plateletcrit ( 27863252) Serum thyroid-stimulating hormone levels ( 24852370) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335) Thyroid volume ( 21565293)
Interacting Genes		8 interacting genes: BCCIP HSPA8 MRPL20 MTPN PTN RPP14 SIRPA VHL	17 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDKN1A CSNK2B H2BC15 ITSN2 PTN PTPRM RAD51 RPL23 SRC TENT5A TP53 YY1
Entrez ID		832	56647
HPRD ID		11872	16542
Ensembl ID		ENSG00000077549	ENSG00000107949
Uniprot IDs		A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0	Q9P287
PDB IDs
Enriched GO Terms of Interacting Partners?
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