BCCIP and CAPZB

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BCCIP	CAPZB
Description		BRCA2 and CDKN1A interacting protein	capping actin protein of muscle Z-line subunit beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Cytosol Cytoskeleton F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Extracellular Exosome WASH Complex
	Molecular Function	RNA Binding Protein Binding Tubulin Binding Kinase Regulator Activity	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization DNA Repair Cellular Response To DNA Damage Stimulus Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	Cell Morphogenesis ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly
Pathways			MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Plateletcrit ( 27863252) Serum thyroid-stimulating hormone levels ( 24852370) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335) Thyroid volume ( 21565293)
Interacting Genes		17 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDKN1A CSNK2B H2BC15 ITSN2 PTN PTPRM RAD51 RPL23 SRC TENT5A TP53 YY1	8 interacting genes: BCCIP HSPA8 MRPL20 MTPN PTN RPP14 SIRPA VHL
Entrez ID		56647	832
HPRD ID		16542	11872
Ensembl ID		ENSG00000107949	ENSG00000077549
Uniprot IDs		Q9P287	A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0
PDB IDs
Enriched GO Terms of Interacting Partners?
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