SYMPK and CSTF2

Number of citations of the paper that reports this interaction (PubMedID 10669729)
100

Data Source:
HPRD (in vitro)

		SYMPK	CSTF2
Description		symplekin	cleavage stimulation factor subunit 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Nuclear Stress Granule	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Export From Nucleus Cell Adhesion MRNA 3'-end Processing Negative Regulation Of Protein Binding Positive Regulation Of Protein Dephosphorylation	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Colon cancer ( 28295283) Colorectal cancer ( 28295283) Coronary artery disease ( 29212778) Eosinophil counts ( 27863252)
Interacting Genes		7 interacting genes: CSTF2 HSF1 HTT RIN3 TOP1 UBE2I YBX3	23 interacting genes: APP BAG6 CEP126 CHD3 CSTF3 DDX1 ECH1 EEF1G ELP1 ERG28 FEZ1 HGS IMMT KAT5 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341
Entrez ID		8189	1478
HPRD ID		09090	02652
Ensembl ID		ENSG00000125755	ENSG00000101811
Uniprot IDs		A0A024R0R6 Q92797	B3V096 B4DUD5 E7EWR4 P33240
PDB IDs		3O2Q 3O2S 3O2T 3ODR 3ODS 4H3H 4H3K	1P1T 2J8P
Enriched GO Terms of Interacting Partners?
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