TSGA10 and PRPF31

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		TSGA10	PRPF31
Description		testis specific 10	pre-mRNA processing factor 31
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Centriole Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece	Nucleus Nucleoplasm U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome MLL1 Complex Spliceosomal Tri-snRNP Complex
	Molecular Function	Molecular_function Protein Binding	RNA Binding Protein Binding U4 SnRNA Binding U4atac SnRNA Binding Ribonucleoprotein Complex Binding SnRNP Binding
	Biological Process	Spermatogenesis Cell Projection Assembly	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome SnoRNA Localization Ribonucleoprotein Complex Localization
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Bipolar disorder ( 21926972) Intelligence (MTAG) ( 29326435)	Change in HbA1c levels in response to metformin treatment in type 2 diabetes ( 29650774)
Interacting Genes		42 interacting genes: AXIN1 BCL6B BIRC2 CBX8 CBY2 CCDC33 CCHCR1 CDC73 CDK18 CEP44 CEP57L1 CREB5 FAM161A FBF1 GCC2-AS1 HIF1A KRT6A LMNA MID2 PPHLN1 PPP1R18 PRPF31 RCOR3 RNF6 RTP5 SCEL SYT6 TCEA2 TLE5 TRIM29 ZBTB24 ZBTB38 ZNF124 ZNF2 ZNF410 ZNF417 ZNF426 ZNF490 ZNF544 ZNF587 ZNF599 ZNF670	76 interacting genes: C1QTNF1 CALCOCO2 CBY2 CCDC136 CCDC33 CCDC57 CCNDBP1 CDCA7L CEP70 DVL2 EFEMP2 FANCA FANCC FASTK GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 LZTS2 MDFI MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NCAPH2 NDUFB9 NOTCH2NLA PAK5 PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PSTPIP1 RACK1 RBM25 RBM4 RBMX RBMY1A1 RBMY1F RINT1 SIAH1 SNRNP200 SSX2IP STX11 TADA2A TFIP11 TLE5 TMCC2 TP53BP2 TRIM27 TRIM41 TSGA10 USP15 ZFP64 ZNF24 ZNF250 ZNF408 ZNF417 ZNF473 ZNF587
Entrez ID		80705	26121
HPRD ID		06202	05917
Ensembl ID		ENSG00000135951	ENSG00000105618
Uniprot IDs		A0A218MIY9 Q9BZW7	Q8WWY3
PDB IDs			2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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