CCDC6 and PPP4C

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CCDC6	PPP4C
Description		coiled-coil domain containing 6	protein phosphatase 4 catalytic subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Biological_process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling
Pathways			Processing of DNA double-strand break ends
Drugs
Diseases		Thyroid cancer
GWAS		Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)
Interacting Genes		7 interacting genes: ATF2 CREB1 CSNK2A1 FBXW7 MAPK3 PPP4C UBE2I	21 interacting genes: CCDC6 DHX38 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6 TRIM28
Entrez ID		8030	5531
HPRD ID		09064	03615
Ensembl ID		ENSG00000108091	ENSG00000149923
Uniprot IDs		Q05CP8 Q16204	A0A024R625 P60510
PDB IDs
Enriched GO Terms of Interacting Partners?
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