GRPEL1 and NKX3-2

		GRPEL1	NKX3-2
Description		GrpE like 1, mitochondrial	NK3 homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Nucleoplasm Mitochondrion Mitochondrial Matrix	Nuclear Chromatin Nucleus
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Protein Folding Protein Import Into Mitochondrial Matrix Regulation Of Catalytic Activity	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Transcription By RNA Polymerase II Determination Of Left/right Symmetry Cell Differentiation Pancreas Development Negative Regulation Of Chondrocyte Differentiation Middle Ear Morphogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Spleen Development Animal Organ Formation Skeletal System Morphogenesis Embryonic Skeletal System Development Intestinal Epithelial Cell Development
Pathways		Mitochondrial protein import	Regulation of RUNX2 expression and activity
Drugs
Diseases			Spondylo-megaepiphyseal-metaphyseal dysplasia
GWAS			Metabolite levels ( 23823483) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		8 interacting genes: DSP FAM184B FGFBP2 MED28 NKX3-2 SFTPB WBP2 XYLB	4 interacting genes: GRPEL1 HDAC1 SMAD1 SMAD4
Entrez ID		80273	579
HPRD ID		07550	09075
Ensembl ID		ENSG00000109519	ENSG00000109705
Uniprot IDs		Q9HAV7	P78367
PDB IDs
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