NKX3-2 and GRPEL1

		NKX3-2	GRPEL1
Description		NK3 homeobox 2	GrpE like 1, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	PAM Complex, Tim23 Associated Import Motor Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Transcription By RNA Polymerase II Determination Of Left/right Symmetry Cell Differentiation Pancreas Development Negative Regulation Of Chondrocyte Differentiation Middle Ear Morphogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Spleen Development Animal Organ Formation Skeletal System Morphogenesis Embryonic Skeletal System Development Intestinal Epithelial Cell Development	Protein Folding Protein Import Into Mitochondrial Matrix Regulation Of Catalytic Activity
Pathways		Regulation of RUNX2 expression and activity	Mitochondrial protein import
Drugs
Diseases		Spondylo-megaepiphyseal-metaphyseal dysplasia
GWAS		Metabolite levels ( 23823483) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		4 interacting genes: GRPEL1 HDAC1 SMAD1 SMAD4	8 interacting genes: DSP FAM184B FGFBP2 MED28 NKX3-2 SFTPB WBP2 XYLB
Entrez ID		579	80273
HPRD ID		09075	07550
Ensembl ID		ENSG00000109705	ENSG00000109519
Uniprot IDs		P78367	Q9HAV7
PDB IDs
Enriched GO Terms of Interacting Partners?
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