NUP214 and DDX19B

Number of citations of the paper that reports this interaction (PubMedID 10428971)
103

Data Source:
HPRD (in vitro)

		NUP214	DDX19B
Description		nucleoporin 214	DEAD-box helicase 19B
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GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytosol Host Cell Cytoplasmic Side Of Nuclear Pore	Nucleus Nuclear Pore Cytoplasm Cytoplasmic Stress Granule Membrane Nuclear Membrane Extracellular Exosome
	Molecular Function	Nuclear Export Signal Receptor Activity Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of MRNA Stability Regulation Of Nucleocytoplasmic Transport Regulation Of Cell Cycle Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins HuR (ELAVL1) binds and stabilizes mRNA SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 31219225)	Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 30578418)
Interacting Genes		29 interacting genes: APC ASS1 CHST6 CLEC4G DDX19B DYNC1I1 IPO5 LSS MRPS6 NCBP1 NUP107 NUP42 NUP62 NUP88 NUP98 NXF1 NXF2 POMT1 PRRX2 SMAD2 SMAD3 SMAD4 STOM TNPO1 VAV2 XPO1 XPO5 XPOT ZFP36	14 interacting genes: APP B3GALT4 DCK IKBKG MIF4GD NUP214 POT1 PRPSAP1 RACK1 RWDD2B SKP1 TERF1 UBC XPO7
Entrez ID		8021	11269
HPRD ID		00258	05781
Ensembl ID		ENSG00000126883	ENSG00000157349
Uniprot IDs		B7ZAV2 P35658	A0A024QZ90 A0A0U4B4U6 B4DL69 Q9UMR2
PDB IDs		2OIT 3FHC 3FMO 3FMP 5DIS	3EWS 3FHC 3FHT 3FMO 3FMP 3G0H 6B4I 6B4J 6B4K
Enriched GO Terms of Interacting Partners?
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