CENPT and CYB5B

		CENPT	CYB5B
Description		centromere protein T	cytochrome b5 type B
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Heterodimerization Activity	Protein Binding Enzyme Activator Activity Heme Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Chromosome Segregation CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly	Xenobiotic Metabolic Process Positive Regulation Of Catalytic Activity Oxidation-reduction Process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Phase I - Functionalization of compounds
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Schizophrenia ( 25056061 29483656)	Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		9 interacting genes: APP CENPW COPS5 CYB5B DHX29 H3C1 PPCDC SNCB TCEA2	11 interacting genes: APP B3GNT9 C16orf70 CENPT CLN8 COG8 CREB3 ESRP2 LMNA RPS2P45 SLC7A6OS
Entrez ID		80152	80777
HPRD ID		07811	13106
Ensembl ID		ENSG00000102901	ENSG00000103018
Uniprot IDs		B3KPB2 Q96BT3	O43169
PDB IDs			3NER
Enriched GO Terms of Interacting Partners?
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